2-(Diethylamino)ethanethiol

Basic Information

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CAS Number

100-38-9

Molecular Formula

C6H15NS

Molecular Weight

133.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Refractive Index

1.5500 (estimate)

SMILES

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CCN(CC)CCS

InChI

InChI=1S/C6H15NS/c1-3-7(4-2)5-6-8/h8H,3-6H2,1-2H3

InChIKey

YBDSNEVSFQMCTL-UHFFFAOYSA-N

LogP

1.258

Topological Polar Surface Area

3.24 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

43.8

Synonyms & References

English

beta-Diethylaminoethyl mercaptan
Diethylcysteamine
N-Diethyl cysteamine
2-(diethylamino)-ethanethiol
BRN 0773677
Triethylamine, 2-mercapto-
2-(N,N-Diethylamino)ethanethiol
N,N-Diethyl-cysteamine
N,N-diethylaminoethylmercaptan
NSC 49193
2-diethylamino-ethanethiol
N-Diaethyl cysteamin
N,N-Diethylcysteamine
DTXSID1074414
.beta.-Diethylaminoethyl mercaptan
100-38-9
Diethylcysteamin
4-04-00-01590 (Beilstein Handbook Reference)
H-D-METYR-OHHCL
F8881-2878
2-(Diethylamino)ethanethiol
2-(diethylamino)ethane-1-thiol
NSC-49193
UNII-TF6S7Q84YD
2-(diethylamino)-ethanthiol
diethyl(2-sulfanylethyl)amine
WLN: SH2N2 & 2
EINECS 202-846-8
FT-0612167
N-Diaethyl cysteamin [German]
2-Diethylaminoethanethiol

MDL Number

MFCD00066258

Customs Code

2942000000

FAQ

What are the physical and chemical properties of 2-(Diethylamino)ethanethiol (CAS: 100-38-9)?

2-(Diethylamino)ethanethiol (CAS: 100-38-9) is a colorless, odorless liquid with a molecular weight of approximately 154.24 g/mol. It is slightly soluble in water but highly soluble in organic solvents. The compound is known for its reactivity, particularly its ability to form adducts with metal ions. It has a low viscosity and is a strong nucleophile, making it useful in organic synthesis and as a protective group reagent.

How is 2-(Diethylamino)ethanethiol (CAS: 100-38-9) typically synthesized?

2-(Diethylamino)ethanethiol is commonly synthesized via the reaction of 2-bromoethanethiol with diethylamine. This process involves the substitution of a bromine atom in 2-bromoethanethiol with a diethylamino group. The reaction can be catalyzed by various bases and is typically carried out in non-polar solvents to achieve high yields and good selectivity.

What industries use 2-(Diethylamino)ethanethiol (CAS: 100-38-9)?

2-(Diethylamino)ethanethiol finds applications in several industries. It is utilized in pharmaceuticals for the synthesis of drug intermediates, in polymers as a stabilizer, and in the manufacturing of sensors for detecting metal ions. Additionally, it is used in the electronics industry as a precursor for semiconductor materials due to its ability to form stable adducts with metal ions.

What precautions should be taken when handling 2-(Diethylamino)ethanethiol (CAS: 100-38-9)?

When handling 2-(Diethylamino)ethanethiol (CAS: 100-38-9), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and lab coat. This compound is corrosive and can irritate the skin and eyes. It should be used in a well-ventilated area or a fume hood to minimize inhalation risks. In case of a spill, neutralize the area with a base and dispose of it according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.