N-Methyl-4-nitroaniline | CAS No. 100-15-2

Q: What is N-Methyl-4-nitroaniline (CAS: 100-15-2)?

N-Methyl-4-nitroaniline (CAS: 100-15-2) is an aromatic amine compound with the chemical formula C7H8N2O2. It features a benzene ring substituted with a nitro group at the 4-position and an N-methyl group on the amino moiety. This compound is typically a yellow solid with moderate solubility in water and organic solvents. Its structure makes it valuable in various chemical applications due to its reactivity and functional groups.

Q: What are the main uses of N-Methyl-4-nitroaniline (CAS: 100-15-2)?

N-Methyl-4-nitroaniline (CAS: 100-15-2) is primarily used as a precursor in pharmaceutical synthesis, dye manufacturing, and organic chemistry research. It plays a role in the development of drugs and agrochemicals due to its ability to undergo nitro group reduction and methylation reactions. Additionally, it serves as an intermediate in the production of azo compounds and other nitrogen-containing chemicals, contributing to industrial and academic applications.

Q: Is N-Methyl-4-nitroaniline (CAS: 100-15-2) safe?

N-Methyl-4-nitroaniline (CAS: 100-15-2) requires careful handling due to potential toxicity. It may cause irritation to the skin, eyes, and respiratory system, and is classified as a hazardous substance under certain safety regulations. Precautions include wearing protective gloves, goggles, and a lab coat, and working in a well-ventilated area. Always follow OSHA and EPA guidelines for exposure limits and proper disposal to ensure safety.

Q: How should N-Methyl-4-nitroaniline (CAS: 100-15-2) be stored?

N-Methyl-4-nitroaniline (CAS: 100-15-2) should be stored in a cool, dry, and dark place, ideally at 15-25°C. Keep it in a sealed, airtight container to prevent moisture absorption and degradation. Avoid exposure to strong oxidizing agents or incompatible materials. Ensure storage in a well-ventilated area to maintain stability and minimize health risks.

N-Methyl-4-nitroaniline

Basic Information

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CAS Number

100-15-2

Molecular Formula

C7H8N2O2

Molecular Weight

152.15 g/mol

EINECS

202-823-2

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Yellow to Very Dark Yellow

Melting Point

149-151°C

Boiling Point

294.61°C (rough estimate)

Density

1.2010

Water Solubility

<0.1 g/100 mL at 19 ºC

Flash Point

129.5±22.6 °C

Solubility

Chloroform (Slightly), Methanol (Slightly)

Refractive Index

1.6276 (estimate)

Vapor Pressure

0.0±0.6 mmHg at 25°C

Vapor Density

5.25 (vs air)

SMILES

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CNC1=CC=C(C=C1)[N+](=O)[O-]

InChI

InChI=1S/C7H8N2O2/c1-8-6-2-4-7(5-3-6)9(10)11/h2-5,8H,1H3

InChIKey

XIFJZJPMHNUGRA-UHFFFAOYSA-N

LogP

2.23270

pKa

0.56±0.12(Predicted)

Complexity

136

Safety Information

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GHS Hazard Pictograms

H373

Hazard Statement

H373 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure

Hazard Class

Class 6.1 Class 6.1

Stability

Stable. Combustible. Incompatible with strong oxidizing agents.

Synonyms & References

English

DTXCID605635
(4-nitro-phenyl)-methylamine
W-109374
NSC 5390
p-(N-methylamino)nitrobenzene
N-methyl(4-nitrophenyl)amine
SMR001370918
N-Methyl-N-(4-nitrophenyl)amine #
AKOS002312303
SCHEMBL12707572
4-Nitro-N-methylaniline
N-(4-nitrophenyl)-N-methylaniline
CS-0011554
N-METHYL-4-NITROBENZENAMINE
A800059
N-Methyl-4-nitroaniline
4-methylamino-nitrobenzene
STR06194
N-(4-Nitrophenyl)-N-methylamine
M1011
N-Methyl-p-nitroaniline
methyl(4-nitrophenyl)amine
NCGC00257555-01
FT-0629710
AC-907/25014172
NSC-5390
N-Methyl-p-nitraniline
BCP04516
p-(Methylamino)nitrobenzene
J836WLV9BW
Aniline, N-methyl-p-nitro-

MDL Number

MFCD00007305

EC Number

202-823-2

Customs Code

29214200

FAQ

What is N-Methyl-4-nitroaniline (CAS: 100-15-2)?

N-Methyl-4-nitroaniline (CAS: 100-15-2) is an aromatic amine compound with the chemical formula C7H8N2O2. It features a benzene ring substituted with a nitro group at the 4-position and an N-methyl group on the amino moiety. This compound is typically a yellow solid with moderate solubility in water and organic solvents. Its structure makes it valuable in various chemical applications due to its reactivity and functional groups.

What are the main uses of N-Methyl-4-nitroaniline (CAS: 100-15-2)?

N-Methyl-4-nitroaniline (CAS: 100-15-2) is primarily used as a precursor in pharmaceutical synthesis, dye manufacturing, and organic chemistry research. It plays a role in the development of drugs and agrochemicals due to its ability to undergo nitro group reduction and methylation reactions. Additionally, it serves as an intermediate in the production of azo compounds and other nitrogen-containing chemicals, contributing to industrial and academic applications.

Is N-Methyl-4-nitroaniline (CAS: 100-15-2) safe?

N-Methyl-4-nitroaniline (CAS: 100-15-2) requires careful handling due to potential toxicity. It may cause irritation to the skin, eyes, and respiratory system, and is classified as a hazardous substance under certain safety regulations. Precautions include wearing protective gloves, goggles, and a lab coat, and working in a well-ventilated area. Always follow OSHA and EPA guidelines for exposure limits and proper disposal to ensure safety.

How should N-Methyl-4-nitroaniline (CAS: 100-15-2) be stored?

N-Methyl-4-nitroaniline (CAS: 100-15-2) should be stored in a cool, dry, and dark place, ideally at 15-25°C. Keep it in a sealed, airtight container to prevent moisture absorption and degradation. Avoid exposure to strong oxidizing agents or incompatible materials. Ensure storage in a well-ventilated area to maintain stability and minimize health risks.