How is 4-bromo-N,N-diethyl-naphthalene-1-carboxamide (CAS: 1199773-48-2) typically synthesized?

4-Bromo-N,N-diethyl-naphthalene-1-carboxamide (CAS: 1199773-48-2) can be synthesized via the acylation of 4-bromonaphtalene-1-carboxylic acid with diethylamine. This process typically involves using an appropriate base, such as sodium hydride, in an aprotic solvent like dimethylformamide (DMF). The reaction is usually carried out under inert conditions to ensure high yield and selectivity. The product is then purified using column chromatography.