Compound Q&A
How is (2S)-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)[2-(trifluoromethyl)phenyl]acetic acid (CAS: 1203454-45-8) typically synthesized?
Answer
![(2S)-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)[2-(trifluoromethyl)phenyl]acetic acid](https://static.chemtradehub.com/structs/120/1203454-45-8-4ee2.webp "(2S)-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)[2-(trifluoromethyl)phenyl]acetic acid")
The compound is usually synthesized via a multistep process involving acylation and amidation reactions. Commonly used catalysts include N,N-dimethylaminopyridine (DMAP), and the synthesis typically achieves a yield of about 75%. The reaction involves the coupling of 2-(trifluoromethyl)phenyl acetic acid with 2-methyl-2-propanol under basic conditions.
About
CAS No
1203454-45-8
English Name
(2S)-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)[2-(trifluoromethyl)phenyl]acetic acid
Molecular Formula
C14H16F3NO4
Molecular Weight
319.276354789734 g/mol
SMILES
FC(C1C=CC=CC=1[C@@H](C(=O)O)NC(=O)OC(C)(C)C)(F)F
InChIKey
DHJLBUSFXBGSRT-JTQLQIEISA-N
Last Updated: 2026-03-29 08:05
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