Compound Q&A
How is 5-Phenyl-2,2'-bipyridine (CAS: 156972-80-4) typically synthesized?
Answer
5-Phenyl-2,2'-bipyridine is commonly synthesized via the condensation of 2,2'-bipyridine with phenyl isocyanate in the presence of a base such as triethylamine. The reaction is carried out at room temperature, and the yield is typically around 70-80%. The use of a fume hood is essential to handle the isocyanate due to its toxicity and volatility.
About
CAS No
156972-80-4
English Name
5-Phenyl-2,2'-bipyridine
Molecular Formula
C16H12N2
Molecular Weight
232.28599999999997 g/mol
SMILES
C1=CC=C(C=C1)C2=CN=C(C=C2)C3=CC=CC=N3
InChIKey
OPPMNBYHIZCEGC-UHFFFAOYSA-N
Last Updated: 2026-03-29 04:03
