How is (2R)-2-(3-Bromophenyl)pyrrolidine hydrochloride (CAS: 1391550-13-2) typically synthesized?

(2R)-2-(3-Bromophenyl)pyrrolidine hydrochloride is typically synthesized through the reaction of 3-bromophenylboronic acid with pyrrolidine in the presence of a palladium catalyst and a base. The reaction conditions, such as the choice of catalyst and base, can significantly affect the yield and selectivity. This method is commonly used in the organic synthesis industry to produce this compound with good efficiency.