Compound Q&A
How is 5-Tert-butyl-1,2,4-oxadiazole-3-carboxylic acid (CAS: 748743-73-9) typically synthesized?
Answer
5-Tert-butyl-1,2,4-oxadiazole-3-carboxylic acid is typically synthesized by reacting tert-butyl isothiocyanate with sodium oxalyl hydrazide. The reaction is conducted in a suitable solvent, often dimethylformamide (DMF). The process involves the formation of an intermediate isothiocyanate, followed by its reaction with sodium oxalyl hydrazide to yield the final product. Yield is generally around 70-80%.
About
CAS No
748743-73-9
English Name
5-Tert-butyl-1,2,4-oxadiazole-3-carboxylic acid
Molecular Formula
C7H10N2O3
Molecular Weight
170.17 g/mol
SMILES
CC(C)(C)C1=NC(=NO1)C(=O)O
InChIKey
FHJXCPARNFHMSZ-UHFFFAOYSA-N
Last Updated: 2026-03-23 00:14
