Compound Q&A
How is Ethyl (2E)-3-(5-fluoro-2-hydroxyphenyl)acrylate (CAS: 949449-09-6) typically synthesized?
Answer
Ethyl (2E)-3-(5-fluoro-2-hydroxyphenyl)acrylate is synthesized through the reaction of 5-fluoro-2-hydroxybenzaldehyde with acryloyl chloride in the presence of a Lewis acid catalyst, such as aluminum trichloride. The reaction yields a high yield of the desired product with good selectivity.
About
CAS No
949449-09-6
English Name
Ethyl (2E)-3-(5-fluoro-2-hydroxyphenyl)acrylate
Molecular Formula
C11H11FO3
Molecular Weight
210.20399999999998 g/mol
SMILES
CCOC(=O)C=CC1=C(C=CC(=C1)F)O
InChIKey
WPJUITWUKANQHJ-ZZXKWVIFSA-N
Last Updated: 2026-03-22 14:59
