Compound Q&A
How is Ethyl 2-(4-fluorophenyl)-5-hydroxy-1-benzofuran-3-carboxylate (CAS: 691856-86-7) typically synthesized?
Answer
Ethyl 2-(4-fluorophenyl)-5-hydroxy-1-benzofuran-3-carboxylate is typically synthesized via a multistep process involving the synthesis of 4-fluorophenylacetic acid, its esterification with ethyl bromide, followed by benzylation and condensation reactions. Commonly used catalysts include sulfuric acid or phosphoryl chloride. The final product shows high selectivity and yield, making it suitable for further medicinal chemistry applications.
About
CAS No
691856-86-7
English Name
Ethyl 2-(4-fluorophenyl)-5-hydroxy-1-benzofuran-3-carboxylate
Molecular Formula
C17H13FO4
Molecular Weight
300.29 g/mol
SMILES
CCOC(=O)C1=C(OC2=C1C=C(C=C2)O)C3=CC=C(C=C3)F
InChIKey
PCOIFIVNARQEPO-UHFFFAOYSA-N
Last Updated: 2026-03-16 13:10
