Compound Q&A

How is Methyl 2-(2-amino-1,3-thiazol-4-yl)-2-pentenoate hydrochloride (CAS: 140128-28-5) typically synthesized?

Answer

Methyl 2-(2-amino-1,3-thiazol-4-yl)-2-pentenoate hydrochloride (1:1)
Methyl 2-(2-amino-1,3-thiazol-4-yl)-2-pentenoate hydrochloride is typically synthesized via a multi-step process involving the condensation of 2-amino-1,3-thiazole-4-carbaldehyde oxime with methyl 2-cyclohexenecarboxylate followed by hydrochloric acid treatment. The reaction is carried out under mild conditions, and the product has good selectivity and yield, making it suitable for industrial production.

About

English Name Methyl 2-(2-amino-1,3-thiazol-4-yl)-2-pentenoate hydrochloride (1:1)
Molecular Formula C9H13ClN2O2S
Molecular Weight 248.73 g/mol
SMILES CCC=C(C1=CSC(=N1)N)C(=O)OC.Cl
InChIKey ACOBUWCQVBVTGT-UHFFFAOYSA-N
Last Updated: 2026-03-10 19:33

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