Methyl 2-(2-amino-1,3-thiazol-4-yl)-2-pentenoate hydrochloride (1:1)(CAS: 140128-28-5)

Methyl 2-(2-amino-1,3-thiazol-4-yl)-2-pentenoate hydrochloride (CAS: 140128-28-5) is a crystalline compound with a molecular weight of approximately 295.84 g/mol. It has a pKa of about 7.2 and is moderately soluble in water. This compound is reactive towards nucleophiles and can undergo substitution reactions. Its hydrochloride salt form is used in various applications due to its stability and reactivity.

Methyl 2-(2-amino-1,3-thiazol-4-yl)-2-pentenoate hydrochloride is typically synthesized via a multi-step process involving the condensation of 2-amino-1,3-thiazole-4-carbaldehyde oxime with methyl 2-cyclohexenecarboxylate followed by hydrochloric acid treatment. The reaction is carried out under mild conditions, and the product has good selectivity and yield, making it suitable for industrial production.

Methyl 2-(2-amino-1,3-thiazol-4-yl)-2-pentenoate hydrochloride (CAS: 140128-28-5) is primarily used in the pharmaceutical industry for its anti-inflammatory and analgesic properties. It also finds applications in the polymer industry as a functional monomer and in the semiconductor industry as a precursor for thin-film deposition processes.

When handling Methyl 2-(2-amino-1,3-thiazol-4-yl)-2-pentenoate hydrochloride (CAS: 140128-28-5), ensure the use of appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be immediately cleaned up with appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed spill procedures and safety information.