Compound Q&A
How is 6-Isobutyl-2-oxo-1,2-dihydro-4-pyrimidinecarboxylic acid (CAS: 876715-59-2) typically synthesized?
Answer
6-Isobutyl-2-oxo-1,2-dihydro-4-pyrimidinecarboxylic acid can be synthesized via the condensation of isobutyraldehyde and 2-chloro-4-pyrimidinone, followed by amidation. The reaction is typically carried out in the presence of a base such as potassium carbonate, yielding a product with high selectivity and good yield. The method involves careful temperature control to optimize reaction efficiency.
About
CAS No
876715-59-2
English Name
6-Isobutyl-2-oxo-1,2-dihydro-4-pyrimidinecarboxylic acid
Molecular Formula
C9H12N2O3
Molecular Weight
196.21 g/mol
SMILES
CC(C)CC1=CC(=NC(=O)N1)C(=O)O
InChIKey
WDIFSCKLWBVBLR-UHFFFAOYSA-N
Last Updated: 2026-03-08 09:14
