Compound Q&A
How is (1R,5S)-3-Ethylbicyclo[3.2.0]hept-3-en-6-one (CAS: 1235479-61-4) typically synthesized?
Answer
![(1R,5S)-3-Ethylbicyclo[3.2.0]hept-3-en-6-one](https://static.chemtradehub.com/structs/123/1235479-61-4-9ffb.webp "(1R,5S)-3-Ethylbicyclo[3.2.0]hept-3-en-6-one")
(1R,5S)-3-Ethylbicyclo[3.2.0]hept-3-en-6-one is commonly synthesized via a Wittig reaction between ethylmethylphosphonate and 3,7-dimethylbicyclo[3.2.0]hept-3-ene. This method provides good yield (70-80%) and high selectivity. Catalysts such as sodium bis(trimethylsilyl)amide (NTMSA) are employed to enhance reactivity and control the reaction pathway.
About
CAS No
1235479-61-4
English Name
(1R,5S)-3-Ethylbicyclo[3.2.0]hept-3-en-6-one
Molecular Formula
C9H12O
Molecular Weight
136.19 g/mol
SMILES
C(C)C=1C[C@@H]2CC([C@@H]2C1)=O
InChIKey
QEGONAXSXKFDLY-HTQZYQBOSA-N
Last Updated: 2026-03-05 06:57
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