Compound Q&A
How is (5-Amino-2-nitrophenyl)methanol (CAS: 77376-03-5) typically synthesized?
Answer
(5-Amino-2-nitrophenyl)methanol can be synthesized by the nitration of (5-aminophenyl)methanol followed by alcoholysis. Commonly, this involves treating (5-aminophenyl)methanol with nitric acid and sulfuric acid to form the nitro compound, which is then reduced to the alcohol using a reducing agent like sodium borohydride. The overall yield is moderate, and careful control of reaction conditions is necessary.
About
CAS No
77376-03-5
English Name
(5-Amino-2-nitrophenyl)methanol
Molecular Formula
C7H8N2O3
Molecular Weight
168.15 g/mol
SMILES
C1=CC(=C(C=C1N)CO)[N+](=O)[O-]
InChIKey
VHFDIPNKJJLFLN-UHFFFAOYSA-N
Last Updated: 2026-03-04 21:35
