Compound Q&A

How is Akt1 and Akt2-IN-1 (CAS: 893422-47-4) typically synthesized?

Answer

Akt1 and Akt2-IN-1
Akt1 and Akt2-IN-1 (CAS: 893422-47-4) is typically synthesized through a multi-step process involving the condensation of a protected amino acid with a phosphonate ester. The process requires the use of specific catalysts such as HOBt (1-hydroxybenzotriazole) and DCC (dicyclohexylcarbodiimide). The synthetic route is designed to achieve high selectivity and yield, with purification steps including column chromatography and recrystallization.

About

English Name Akt1 and Akt2-IN-1
Molecular Formula C33H29N7O
Molecular Weight 539.64 g/mol
SMILES C1CN(CCC1C2=NC(=NN2)C3=CC=CC=N3)CC4=CC=C(C=C4)C5=C(C=C6C(=N5)C=CNC6=O)C7=CC=CC=C7
InChIKey BTUWHHFNOHVCMQ-UHFFFAOYSA-N
Last Updated: 2026-03-04 16:30

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