Compound Q&A
How is Amikacin EP Impurity B (CAS: 927821-99-6) typically synthesized?
Answer
Amikacin EP Impurity B is synthesized through a series of chemical reactions starting from amikacin or its precursors. The process involves acetylation, amidation, and reduction steps. Commonly, acetic anhydride is used as an acetylating agent, and sodium borohydride serves as the reducing agent. The synthesis yields approximately 70-80% purity of the impurity, with high selectivity towards the desired product.
About
CAS No
927821-99-6
English Name
Amikacin EP Impurity B
Molecular Formula
C26H50N6O15
Molecular Weight
686.71 g/mol
SMILES
C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)NC(=O)C(CCN)O
InChIKey
HVNATBKIPCIZAA-UHFFFAOYSA-N
Last Updated: 2026-01-13 10:36
