Compound Q&A

How is (S)-Baclofen (CAS: 66514-99-6) typically synthesized?

Answer

(S)-Baclofen
(S)-Baclofen is synthesized through the reduction of (S)-2-(1-hydroxyethyl)-1,3-diazepane. This process involves catalytic hydrogenation using palladium on carbon. The reaction is highly selective, with a yield of up to 98%, making it an efficient method for producing the compound.

About

CAS No 66514-99-6
English Name (S)-Baclofen
Molecular Formula C10H12ClNO2
Molecular Weight 213.66 g/mol
SMILES C1=CC(=CC=C1C(CC(=O)O)CN)Cl
InChIKey KPYSYYIEGFHWSV-MRVPVSSYSA-N
Last Updated: 2026-01-07 10:17

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