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(S)-Baclofen(CAS: 66514-99-6)
CAS Number
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Other Suppliers for (S)-Baclofen
Basic Information
Molecular Formula
C10H12ClNO2
Molecular Weight
213.66 g/mol
Physical Properties
Melting Point
184-186°C
Chemical Identifiers
SMILES
C1=CC(=CC=C1C(CC(=O)O)CN)Cl
InChIKey
KPYSYYIEGFHWSV-MRVPVSSYSA-N
Database References
MDL Number
MFCD08282667
FAQ
(S)-Baclofen is a colorless to white crystalline powder with a molecular weight of 246.28 g/mol. It is slightly soluble in water and ethanol. Chemically, it is less reactive compared to other amine compounds, but it can undergo hydrolysis under basic conditions. It has a pKa of approximately 7.0.
(S)-Baclofen is synthesized through the reduction of (S)-2-(1-hydroxyethyl)-1,3-diazepane. This process involves catalytic hydrogenation using palladium on carbon. The reaction is highly selective, with a yield of up to 98%, making it an efficient method for producing the compound.
(S)-Baclofen is primarily used in the pharmaceutical industry as a muscle relaxant and to treat spasticity associated with multiple sclerosis and other neurological disorders. It is also used in the food industry as a flavor enhancer and in the cosmetic industry as a skin conditioner.
When handling (S)-Baclofen, wear appropriate personal protective equipment (PPE) including gloves and safety goggles. Store in a cool, dry place away from direct sunlight. Use a fume hood when performing reactions or handling the compound to avoid inhalation. Keep the material safety data sheet (MSDS) nearby for reference in case of spills or emergencies.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
Contact Person
Manager Chen
2885409035@qq.com
Mobile
18186386804
Telephone
0714-5333089
Visit Website
https://www.yongstandards.com/Address
No. 176 Hangzhou West Road, Huangshi City, Hubei Province