Compound Q&A

How is 2-Bromo-5-(chlorosulfonyl)benzoic acid (CAS: 3285-31-2) typically synthesized?

Answer

2-Bromo-5-(chlorosulfonyl)benzoic acid
2-Bromo-5-(chlorosulfonyl)benzoic acid is typically synthesized through the bromination of 5-chlorosulfonylbenzoic acid with bromine in an aqueous solution. The reaction is performed under acidic conditions using concentrated sulfuric acid. The yield is generally high, and the selectivity of the bromination is excellent, due to the inherent reactivity of the sulfonyl chloride group.

About

CAS No 3285-31-2
English Name 2-Bromo-5-(chlorosulfonyl)benzoic acid
Molecular Formula C7H4BrClO4S
Molecular Weight 299.529 g/mol
SMILES C1=CC(=C(C=C1S(=O)(=O)Cl)C(=O)O)Br
InChIKey ZZSQGLFOZUQDAM-UHFFFAOYSA-N
Last Updated: 2026-01-07 05:52

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