Compound Q&A
How is Methyl 4-bromo-5-cyano-2-thiophenecarboxylate (CAS: 648412-60-6) typically synthesized?
Answer
Methyl 4-bromo-5-cyano-2-thiophenecarboxylate is typically synthesized by reacting methyl thiophene-2-carboxylate with acetonitrile in the presence of a catalytic amount of a Lewis acid such as aluminum chloride. The reaction proceeds under reflux conditions, and the product is purified by recrystallization from a suitable solvent.
About
CAS No
648412-60-6
English Name
Methyl 4-bromo-5-cyano-2-thiophenecarboxylate
Molecular Formula
C7H4BrNO2S
Molecular Weight
246.08 g/mol
SMILES
COC(=O)C1=CC(=C(S1)C#N)Br
InChIKey
CLUNERGOTORYPP-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14
