Compound Q&A

How is 4,4'-[(2-Methoxy-1,4-phenylene)di(E)-2,1-ethenediyl]diphenol (CAS: 863918-78-9) typically synthesized?

Answer

4,4'-[(2-Methoxy-1,4-phenylene)di(E)-2,1-ethenediyl]diphenol
4,4'-[(2-Methoxy-1,4-phenylene)di(E)-2,1-ethenediyl]diphenol can be synthesized through a multistep process involving the coupling of 4-bromophenol and 4-bromo-2-methoxyphenol followed by the formation of a diene intermediate. The reaction is typically catalyzed by palladium-based catalysts, and the overall yield is around 80-85%. The process requires careful control of reaction conditions to ensure high selectivity and yield.

About

English Name 4,4'-[(2-Methoxy-1,4-phenylene)di(E)-2,1-ethenediyl]diphenol
Molecular Formula C23H20O3
Molecular Weight 344.41 g/mol
SMILES COc1cc(ccc1/C=C/c2ccc(cc2)O)/C=C/c3ccc(cc3)O
InChIKey FGYNZFHVGOFCMD-KHVHPYDTSA-N
Last Updated: 2026-01-04 19:14

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