4,4'-[(2-Methoxy-1,4-phenylene)di(E)-2,1-ethenediyl]diphenol(CAS: 863918-78-9)

4,4'-[(2-Methoxy-1,4-phenylene)di(E)-2,1-ethenediyl]diphenol is a crystalline solid with a molecular weight of approximately 434.36 g/mol. It has low water solubility and moderate solubility in common organic solvents like dichloromethane and acetonitrile. This compound is relatively chemically stable but can react with strong acids and bases. Its reactivity is primarily influenced by the phenolic hydroxyl groups.

4,4'-[(2-Methoxy-1,4-phenylene)di(E)-2,1-ethenediyl]diphenol can be synthesized through a multistep process involving the coupling of 4-bromophenol and 4-bromo-2-methoxyphenol followed by the formation of a diene intermediate. The reaction is typically catalyzed by palladium-based catalysts, and the overall yield is around 80-85%. The process requires careful control of reaction conditions to ensure high selectivity and yield.

4,4'-[(2-Methoxy-1,4-phenylene)di(E)-2,1-ethenediyl]diphenol is primarily used in the pharmaceutical industry for the development of novel drug candidates. It also finds applications in the production of paints and coatings as a colorant. Additionally, this compound is used in the manufacturing of electronic materials and sensors due to its unique chemical structure and properties.

When handling 4,4'-[(2-Methoxy-1,4-phenylene)di(E)-2,1-ethenediyl]diphenol, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.