Compound Q&A
How is [3-Chloro-5-(4-morpholinylcarbonyl)phenyl]boronic acid (CAS: 957120-55-7) typically synthesized?
Answer
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[3-Chloro-5-(4-morpholinylcarbonyl)phenyl]boronic acid is typically synthesized by coupling 3-chlorophenylboronic acid with 4-(carbonyl)-4-morpholinyl boronic acid in the presence of a palladium catalyst (e.g., Pd(PPh3)4) and a base (e.g., potassium carbonate). The reaction is carried out in an organic solvent like toluene or dioxane at elevated temperatures. High selectivity and yields can be achieved under optimized conditions.
About
CAS No
957120-55-7
English Name
[3-Chloro-5-(4-morpholinylcarbonyl)phenyl]boronic acid
Molecular Formula
C11H13BClNO4
Molecular Weight
269.49 g/mol
SMILES
B(C1=CC(=CC(=C1)Cl)C(=O)N2CCOCC2)(O)O
InChIKey
ZXFMDBGQTVWQQY-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14
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