Compound Q&A

How is (3,4-Difluorophenyl)(hydroxy)acetic acid (CAS: 132741-29-8) typically synthesized?

Answer

(3,4-Difluorophenyl)(hydroxy)acetic acid
(3,4-Difluorophenyl)(hydroxy)acetic acid (CAS: 132741-29-8) can be synthesized through a multi-step process involving the reaction of 3,4-difluorophenol with acetic anhydride, followed by hydrolysis. This method typically yields a product with a purity of over 95%. Commonly, this synthesis is carried out in the presence of a catalyst, such as hydrochloric acid, to increase selectivity and yield. Proper safety measures should be taken during the reaction, including the use of fume hoods and appropriate personal protective equipment.

About

English Name (3,4-Difluorophenyl)(hydroxy)acetic acid
Molecular Formula C8H6F2O3
Molecular Weight 188.13 g/mol
SMILES C1=CC(=C(C=C1C(C(=O)O)O)F)F
InChIKey BKHXODARAOCNDJ-UHFFFAOYSA-N
Last Updated: 2026-01-01 10:50

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