Compound Q&A

How is 4-Nitrophenyl N-[(benzyloxy)carbonyl]-D-phenylalaninate (CAS: 2578-85-0) typically synthesized?

Answer

4-Nitrophenyl N-[(benzyloxy)carbonyl]-D-phenylalaninate
4-Nitrophenyl N-[(benzyloxy)carbonyl]-D-phenylalaninate is typically synthesized via a multistep process involving the coupling of D-phenylalanine with 4-nitrophenyl chloroformate in the presence of a base like triethylamine. The reaction yields the desired product with good selectivity and moderate to high yield, depending on the reaction conditions.

About

CAS No 2578-85-0
English Name 4-Nitrophenyl N-[(benzyloxy)carbonyl]-D-phenylalaninate
Molecular Formula C23H20N2O6
Molecular Weight 420.4 g/mol
SMILES C1=CC=C(C=C1)CC(C(=O)OC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)OCC3=CC=CC=C3
InChIKey TVENQUPLPBPLGU-OAQYLSRUSA-N
Last Updated: 2025-12-31 11:48

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