Compound Q&A

How is 4-Amino-2,5-dimethoxy-N-methylbenzenesulfonamide (CAS: 49701-24-8) typically synthesized?

Answer

4-Amino-2,5-dimethoxy-N-methylbenzenesulfonamide
4-Amino-2,5-dimethoxy-N-methylbenzenesulfonamide (CAS: 49701-24-8) is typically synthesized by the reaction of 2,5-dimethoxy-N-methylbenzenesulfonyl chloride with ammonia in the presence of a base such as sodium hydroxide. The reaction is carried out under mild conditions, and the product is isolated by filtration and recrystallization. The yield is usually around 85%, and the reaction is highly selective, making it a reliable method for its preparation.

About

CAS No 49701-24-8
English Name 4-Amino-2,5-dimethoxy-N-methylbenzenesulfonamide
Molecular Formula C9H14N2O4S
Molecular Weight 246.29 g/mol
SMILES CNS(=O)(=O)C1=C(C=C(C(=C1)OC)N)OC
InChIKey CISVVDNATRQDNU-UHFFFAOYSA-N
Last Updated: 2025-12-31 11:48

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