Compound Q&A
How is Ethyl 5-chloro-4-nitrothiophene-2-carboxylate (CAS: 89640-03-9) typically synthesized?
Answer
Ethyl 5-chloro-4-nitrothiophene-2-carboxylate is typically synthesized from 5-chloro-4-nitrothiophene and ethyl chloroformate using triethylamine as a base. The reaction is carried out in an organic solvent like dichloromethane under stirring and cooling. The yield is usually around 70-80%, and the product can be purified by recrystallization.
About
CAS No
89640-03-9
English Name
Ethyl 5-chloro-4-nitrothiophene-2-carboxylate
Molecular Formula
C7H6ClNO4S
Molecular Weight
235.64 g/mol
SMILES
CCOC(=O)C1=CC(=C(S1)Cl)[N+](=O)[O-]
InChIKey
VJKXMTCBMRGJIE-UHFFFAOYSA-N
Last Updated: 2025-12-28 19:55
