Compound Q&A
How is (1R,3R,4S)-4-((tert-Butyldimethylsilyl)oxy)-3-(((tert-butyldimethylsilyl)-oxy)methyl)-2-methylenecyclopentanol (CAS: 701278-56-0) typically synthesized?
Answer
The compound is synthesized through a multi-step process involving silylation and methylenation reactions. A common method involves the use of tert-butyldimethylsilyl chloride and tert-butyldimethylsilyl triflate as the silylating agents. The reaction is typically performed under anhydrous conditions to prevent side reactions. The yield is usually around 70-80%, with good selectivity towards the desired stereochemistry.
About
CAS No
701278-56-0
English Name
(1R,3R,4S)-4-((tert-Butyldimethylsilyl)oxy)-3-(((tert-butyldimethylsilyl)-oxy)methyl)-2-methylenecyclopentanol
Molecular Formula
C19H40O3Si2
Molecular Weight
372.7 g/mol
SMILES
CC(C)(C)[Si](C)(C)OCC1C(CC(C1=C)O)O[Si](C)(C)C(C)(C)C
InChIKey
ITBIDWSGCHAPLY-BBWFWOEESA-N
Last Updated: 2025-12-28 10:59
