Compound Q&A
How is 1-(2-Methyl-2-propanyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one (CAS: 1455358-06-1) typically synthesized?
Answer
![1-(2-Methyl-2-propanyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one](https://static.chemtradehub.com/structs/145/1455358-06-1-e4a8.webp "1-(2-Methyl-2-propanyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one")
1-(2-Methyl-2-propanyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one is typically synthesized through a multi-step process involving the condensation of an appropriate pyridine derivative with an acylating agent. Common catalysts include titanium(IV) isopropoxide, and the reaction proceeds with good selectivity and yield. The final product is purified by recrystallization or column chromatography.
About
CAS No
1455358-06-1
English Name
1-(2-Methyl-2-propanyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
Molecular Formula
C11H14N2O
Molecular Weight
190.25 g/mol
SMILES
O=C1Cc2c(N1C(C)(C)C)nccc2
InChIKey
YCMRNCFOTBJUGG-UHFFFAOYSA-N
Last Updated: 2025-12-28 10:59
![1-(2-Methyl-2-propanyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one — ShangHaiJiZhiShengHua Technology Co Ltd](https://static.chemtradehub.com/suppliers/67cecbee2b2de6e8e95a5b72/67cecbee2b2de6e8e95a5b72-logo.webp){kind=logo}
![1-(2-Methyl-2-propanyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}
![1-(2-Methyl-2-propanyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one — ShenZhenZhenJiangShengWuJiShu Co Ltd](https://static.chemtradehub.com/suppliers/67cec9142b2de6e8e95a51e7/67cec9142b2de6e8e95a51e7-logo.webp){kind=logo}