Compound Q&A
How is 1-Benzyl 2-(4-nitrophenyl) (2S)-1,2-pyrrolidinedicarboxylate (CAS: 3304-59-4) typically synthesized?
Answer
1-Benzyl 2-(4-nitrophenyl) (2S)-1,2-pyrrolidinedicarboxylate (CAS: 3304-59-4) is typically synthesized via a multistep process involving the condensation of 1-benzylpyrrolidine-2,3-dicarboxylic acid with 4-nitrophenyl boronic acid under palladium catalysis. Commonly used catalysts include Pd(PPh3)4 and B2pin2. The reaction yields the desired compound with good selectivity and is performed under mild conditions to avoid side reactions.
About
CAS No
3304-59-4
English Name
1-Benzyl 2-(4-nitrophenyl) (2S)-1,2-pyrrolidinedicarboxylate
Molecular Formula
C19H18N2O6
Molecular Weight
370.4 g/mol
SMILES
C1CC(N(C1)C(=O)OCC2=CC=CC=C2)C(=O)OC3=CC=C(C=C3)[N+](=O)[O-]
InChIKey
GXUFIJVKXYWCAO-KRWDZBQOSA-N
Last Updated: 2025-12-26 02:37
