Compound Q&A
How is 3-(Difluoromethoxy)-2,4,5-trifluorobenzoic acid (CAS: 128426-86-8) typically synthesized?
Answer
3-(Difluoromethoxy)-2,4,5-trifluorobenzoic acid is typically synthesized through a multi-step process involving bromination, substitution, and acylation. Commonly, the synthesis involves reacting 2,4,5-trifluorobenzoic acid with a difluoromethoxy electrophile in the presence of a base and a suitable catalyst to achieve high selectivity and yield.
About
CAS No
128426-86-8
English Name
3-(Difluoromethoxy)-2,4,5-trifluorobenzoic acid
Molecular Formula
C8H3F5O3
Molecular Weight
242.1 g/mol
SMILES
C1=C(C(=C(C(=C1F)F)OC(F)F)F)C(=O)O
InChIKey
XKNIFQLRUBLKKI-UHFFFAOYSA-N
Last Updated: 2025-12-25 13:43
