How is 2,2'-Dibromo-4,4'-diiodobiphenyl (CAS: 852138-93-3) typically synthesized?

2,2'-Dibromo-4,4'-diiodobiphenyl is typically synthesized through the bromination and subsequent iodination of biphenyl using appropriate reagents. The reaction is usually carried out in the presence of a Lewis acid catalyst like aluminum bromide or iron(III) chloride to facilitate the electrophilic aromatic substitution reactions. The yield is generally moderate to high, depending on the reaction conditions.