Compound Q&A
How is (S)-3-(4-Bromophenyl)piperidine (CAS: 1335523-82-4) typically synthesized?
Answer
(S)-3-(4-Bromophenyl)piperidine is typically synthesized via the condensation of 4-bromophenylacetic acid with piperidine, followed by reduction. The reaction is catalyzed by palladium(II) acetate and triphenylphosphine, with good regioselectivity and yield. The process is optimized for high purity and stereoselectivity, making it suitable for pharmaceutical applications.
About
CAS No
1335523-82-4
English Name
(S)-3-(4-Bromophenyl)piperidine
Molecular Formula
C11H14BrN
Molecular Weight
240.14 g/mol
SMILES
Brc1ccc(cc1)[C@@H]1CCCNC1
Last Updated: 2025-11-28 19:29
