Compound Q&A
How is (1R)-1-[3-(Trifluoromethyl)phenyl]ethanol (CAS: 127852-24-8) typically synthesized?
Answer
![(1R)-1-[3-(Trifluoromethyl)phenyl]ethanol](https://static.chemtradehub.com/structs/127/127852-24-8-8270.webp "(1R)-1-[3-(Trifluoromethyl)phenyl]ethanol")
(1R)-1-[3-(Trifluoromethyl)phenyl]ethanol is typically synthesized via a Friedel-Crafts alkylation reaction where ethyl trifluoromethylbenzene is reacted with an alcohol in the presence of a Lewis acid catalyst such as aluminum trichloride. The reaction provides good yield and selectivity, making it a common method for this compound's preparation.
About
CAS No
127852-24-8
English Name
(1R)-1-[3-(Trifluoromethyl)phenyl]ethanol
Molecular Formula
C9H9F3O
Molecular Weight
190.16 g/mol
SMILES
CC(C1=CC(=CC=C1)C(F)(F)F)O
InChIKey
YNVXCOKNHXMBQC-ZCFIWIBFSA-N
Last Updated: 2025-11-28 19:29
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