Compound Q&A
How is 5-Methyl-2-(trifluoromethyl)-3-furoic acid (CAS: 17515-74-1) typically synthesized?
Answer
5-Methyl-2-(trifluoromethyl)-3-furoic acid is typically synthesized via the condensation of methyl trifluoromethyl ketone with formic acid, followed by a Claisen rearrangement. This process often involves the use of a strong base like potassium tert-butoxide. The yield is generally high, and the reaction is known for its good selectivity.
About
CAS No
17515-74-1
English Name
5-Methyl-2-(trifluoromethyl)-3-furoic acid
Molecular Formula
C7H5F3O3
Molecular Weight
194.11 g/mol
SMILES
CC1=CC(=C(O1)C(F)(F)F)C(=O)O
InChIKey
NURNFMNHTHXTDS-UHFFFAOYSA-N
Last Updated: 2025-11-27 19:31
