Compound Q&A

How is (2-Chlorophenyl)methanesulfonyl chloride (CAS: 77421-13-7) typically synthesized?

Answer

(2-Chlorophenyl)methanesulfonyl chloride
(2-Chlorophenyl)methanesulfonyl chloride is usually synthesized by the reaction of 2-chlorophenylmethanol with thionyl chloride in the presence of an appropriate solvent like dichloromethane. This process requires careful temperature control and is often catalyzed to improve yield and selectivity.

About

CAS No 77421-13-7
English Name (2-Chlorophenyl)methanesulfonyl chloride
Molecular Formula C7H6Cl2O2S
Molecular Weight 225.1 g/mol
SMILES C1=CC=C(C(=C1)CS(=O)(=O)Cl)Cl
InChIKey CHPZYFXSICSCNY-UHFFFAOYSA-N
Last Updated: 2025-11-04 22:30

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