Compound Q&A
How is 1,3,3-Trimethyl-6'-(1-piperidinyl)-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine] (CAS: 114747-45-4) typically synthesized?
Answer
![1,3,3-Trimethyl-6'-(1-piperidinyl)-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine]](https://static.chemtradehub.com/structs/114/114747-45-4-cc04.webp "1,3,3-Trimethyl-6'-(1-piperidinyl)-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine]")
This compound is typically synthesized through a multistep reaction involving the condensation of a piperidine derivative with a naphtho[2,1-b][1,4]oxazine-3(4H)-one derivative. The reaction typically uses a Lewis acid catalyst and proceeds with a yield of around 70-80%, depending on the purity of the starting materials and the reaction conditions.
About
CAS No
114747-45-4
English Name
1,3,3-Trimethyl-6'-(1-piperidinyl)-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine]
Molecular Formula
C27H29N3O
Molecular Weight
411.54900000000026 g/mol
SMILES
CN1c2ccccc2C(C21C=Nc1c(O2)cc(c2c1cccc2)N1CCCCC1)(C)C
InChIKey
YAWJWXXKKHOMQT-UHFFFAOYSA-N
Last Updated: 2025-11-04 13:04
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