1,3,3-Trimethyl-6'-(1-piperidinyl)-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine](CAS: 114747-45-4)
![1,3,3-Trimethyl-6'-(1-piperidinyl)-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine] 1,3,3-Trimethyl-6'-(1-piperidinyl)-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine]](https://static.chemtradehub.com/structs/114/114747-45-4-cc04.webp)
CAS Number
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Other Suppliers for 1,3,3-Trimethyl-6'-(1-piperidinyl)-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine]
Basic Information
Molecular Formula
C27H29N3O
Molecular Weight
411.55 g/mol
Physical Properties
Boiling Point
637.2°C at 760 mmHg
Chemical Identifiers
SMILES
CN1c2ccccc2C(C21C=Nc1c(O2)cc(c2c1cccc2)N1CCCCC1)(C)C
InChIKey
YAWJWXXKKHOMQT-UHFFFAOYSA-N
Database References
MDL Number
MFCD00329486
FAQ
The compound has a crystalline form with a molecular weight of approximately 379.45 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is reactive towards nucleophilic substitution and electrophilic addition, with a high degree of stability in neutral conditions.
This compound is typically synthesized through a multistep reaction involving the condensation of a piperidine derivative with a naphtho[2,1-b][1,4]oxazine-3(4H)-one derivative. The reaction typically uses a Lewis acid catalyst and proceeds with a yield of around 70-80%, depending on the purity of the starting materials and the reaction conditions.
This compound is primarily used in the pharmaceutical industry, specifically in the development of new drugs targeting various biological pathways. It is also utilized in the production of sensors and semiconductors, where its unique chemical properties are leveraged for their specific applications.
Handling this compound requires the use of personal protective equipment (PPE) including gloves, goggles, and a lab coat. It should be conducted in a well-ventilated area or under a fume hood. Spills should be handled carefully and neutralized with a suitable base, followed by thorough cleanup. Always refer to the Safety Data Sheet (SDS) for specific handling guidelines.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures

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![1,3,3-Trimethyl-6'-(1-piperidinyl)-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine] — Guangdong Wanzhang Chemical Reagent Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce43292b2de6e8e95a42fd/67ce43292b2de6e8e95a42fd-logo.webp)
![1,3,3-Trimethyl-6'-(1-piperidinyl)-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine] — Hubei Yangxin Pharmaceutical Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cded3957537e5c8069af88/67cded3957537e5c8069af88-logo.webp)
![1,3,3-Trimethyl-6'-(1-piperidinyl)-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine] — Tianjin Fuxin Yangguang Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cec0f22b2de6e8e95a4c56/67cec0f22b2de6e8e95a4c56-logo.webp)
![1,3,3-Trimethyl-6'-(1-piperidinyl)-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine] — Jin Jinle (Hunan) Chemical Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce76192b2de6e8e95a464e/67ce76192b2de6e8e95a464e-logo.webp)
![1,3,3-Trimethyl-6'-(1-piperidinyl)-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine] — ShangHaiJiZhiShengHua Technology Co Ltd](https://static.chemtradehub.com/suppliers/67cecbee2b2de6e8e95a5b72/67cecbee2b2de6e8e95a5b72-logo.webp)