Compound Q&A
How is Diethyl [(4-chlorobenzoyl)amino]malonate (CAS: 81918-01-6) typically synthesized?
Answer
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Diethyl [(4-chlorobenzoyl)amino]malonate is typically synthesized by the reaction of ethyl malonate with 4-chlorobenzoyl chloride in the presence of a tertiary amine like triethylamine as a base. The reaction is conducted at room temperature, and the product is isolated by recrystallization from an appropriate solvent.
About
CAS No
81918-01-6
English Name
Diethyl [(4-chlorobenzoyl)amino]malonate
Molecular Formula
C14H16ClNO5
Molecular Weight
313.74 g/mol
SMILES
CCOC(=O)C(C(=O)OCC)NC(=O)C1=CC=C(C=C1)Cl
InChIKey
KTKBMOLVXVIHQA-UHFFFAOYSA-N
Last Updated: 2025-11-01 22:12
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