Compound Q&A
How is Methyl N-[(2'-cyano-4-biphenylyl)methyl]-L-valinate (CAS: 137863-89-9) typically synthesized?
Answer
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Methyl N-[(2'-cyano-4-biphenylyl)methyl]-L-valinate (CAS: 137863-89-9) is typically synthesized via a multi-step process involving the coupling of 2'-cyano-4-biphenylmethanol with L-valine methyl ester in the presence of a coupling agent like HATU and a base such as DIPEA. The yield is usually around 70-80%, and the reaction is carried out under mild conditions to ensure high selectivity and purity.
About
CAS No
137863-89-9
English Name
Methyl N-[(2'-cyano-4-biphenylyl)methyl]-L-valinate
Molecular Formula
C20H22N2O2
Molecular Weight
311.42500000000007 g/mol
SMILES
CC(C)C(C(=O)OC)NCC1=CC=C(C=C1)C2=CC=CC=C2C#N
InChIKey
ZQHINOUCNQKQEV-IBGZPJMESA-N
Last Updated: 2025-10-31 20:53
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