Compound Q&A
How is Methyl N-Cbz-piperidine-2-carboxylate (CAS: 180609-56-7) typically synthesized?
Answer
Methyl N-Cbz-piperidine-2-carboxylate (CAS: 180609-56-7) is commonly synthesized through the condensation of piperidine-2-carboxylic acid with benzyl chloroformate. The reaction is typically conducted in the presence of a base such as triethylamine. The benzyl protecting group is used to facilitate further functionalization steps in synthetic routes. This method provides good yields and high regioselectivity.
About
CAS No
180609-56-7
English Name
Methyl N-Cbz-piperidine-2-carboxylate
Molecular Formula
C15H19NO4
Molecular Weight
277.31 g/mol
SMILES
COC(=O)C1CCCCN1C(=O)OCC2=CC=CC=C2
InChIKey
PKYPKDMELOKLKL-UHFFFAOYSA-N
Last Updated: 2025-10-31 20:53
