Compound Q&A
How is 2-((5-Bromopyrimidin-2-yl)thio)acetic acid (CAS: 52767-92-7) typically synthesized?
Answer
2-((5-Bromopyrimidin-2-yl)thio)acetic acid is typically synthesized through a multi-step process involving the bromination of pyrimidine followed by thioetherification with acetic acid. Commonly used catalysts include sulfuric acid, and the reaction is conducted under reflux conditions to achieve high yields. The product is purified through recrystallization or column chromatography.
About
CAS No
52767-92-7
English Name
2-((5-Bromopyrimidin-2-yl)thio)acetic acid
Molecular Formula
C6H5BrN2O2S
Molecular Weight
249.09 g/mol
SMILES
C1=C(C=NC(=N1)SCC(=O)O)Br
InChIKey
GEFXJQVEMVQMSS-UHFFFAOYSA-N
Last Updated: 2025-10-31 17:33
