Compound Q&A

How is 2,3-Dihydro-1-benzofuran-7-ylboronic acid (CAS: 685514-61-8) typically synthesized?

Answer

2,3-Dihydro-1-benzofuran-7-ylboronic acid
2,3-Dihydro-1-benzofuran-7-ylboronic acid is typically synthesized through the boronation of 2,3-dihydro-1-benzofuran-7-ylboronic ester using a catalytic system. Common methods include the use of tetrakis(triphenylphosphine)palladium(0) as a catalyst, with triphenylphosphine as a ligand. The reaction proceeds under basic conditions with the boronic acid being generated in situ from the boronic ester. The yield is generally high, around 80-90%, with good selectivity.

About

English Name 2,3-Dihydro-1-benzofuran-7-ylboronic acid
Molecular Formula C8H9BO3
Molecular Weight 163.97 g/mol
SMILES B(C1=C2C(=CC=C1)CCO2)(O)O
InChIKey JDOYUFYZFXCQJP-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16

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