Compound Q&A

How is 3-(Trifluoromethyl)isonicotinic acid (CAS: 590371-38-3) typically synthesized?

Answer

3-(Trifluoromethyl)isonicotinic acid
3-(Trifluoromethyl)isonicotinic acid is commonly synthesized by reacting 3-(trifluoromethyl)isonicotinoyl chloride with a base such as sodium hydroxide or potassium hydroxide in an aqueous medium. The reaction is typically conducted at room temperature with good yield and selectivity.

About

English Name 3-(Trifluoromethyl)isonicotinic acid
Molecular Formula C7H4F3NO2
Molecular Weight 191.11 g/mol
SMILES C1=CN=CC(=C1C(=O)O)C(F)(F)F
InChIKey FBOSFEOQEZQFOC-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16

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