Compound Q&A
How is methyl 6-cyano-1H-indole-2-carboxylate (CAS: 104291-83-0) typically synthesized?
Answer
Methyl 6-cyano-1H-indole-2-carboxylate (CAS: 104291-83-0) is typically synthesized via a multistep process involving the condensation of indole-2-carboxylic acid and cyanoacetamide, followed by esterification with methanol. This reaction can be catalyzed by various Lewis acids or reactive metal catalysts. The yield is typically around 70-80%.
About
CAS No
104291-83-0
English Name
methyl 6-cyano-1H-indole-2-carboxylate
Molecular Formula
C11H8N2O2
Molecular Weight
189.21 g/mol
SMILES
COC(=O)C1=CC2=C(N1)C=C(C=C2)C#N
InChIKey
VDOVWALYWVUEQR-UHFFFAOYSA-N
Last Updated: 2025-10-28 23:23
