Compound Q&A
How is 3-Chloro-2-fluoro-4-iodopyridine (CAS: 796851-05-3) typically synthesized?
Answer
3-Chloro-2-fluoro-4-iodopyridine is typically synthesized via the Friedel-Crafts alkylation of 2-fluoro-4-chloropyridine with iodine in the presence of aluminum chloride as a catalyst. The reaction proceeds through electrophilic aromatic substitution, yielding the desired product with good selectivity and yield.
About
CAS No
796851-05-3
English Name
3-Chloro-2-fluoro-4-iodopyridine
Molecular Formula
C5H2ClFIN
Molecular Weight
257.43 g/mol
SMILES
c1cnc(c(c1I)Cl)F
InChIKey
NPDICENVXROWJV-UHFFFAOYSA-N
Last Updated: 2025-10-28 23:22