Compound Q&A
How is 5-Bromo-2-fluorocinnamic acid (CAS: 202865-71-2) typically synthesized?
Answer
5-Bromo-2-fluorocinnamic acid is synthesized through a series of steps, starting with 2-fluorocinnamic acid. Bromination is achieved using bromine in the presence of a Lewis acid like aluminum bromide. The reaction is typically carried out in an inert solvent like dichloromethane, with a yield of around 70-80% and good selectivity.
About
CAS No
202865-71-2
English Name
5-Bromo-2-fluorocinnamic acid
Molecular Formula
C9H6BrFO2
Molecular Weight
245.05 g/mol
SMILES
C1=CC(=C(C=C1Br)C=CC(=O)O)F
InChIKey
ROTBALNVXDGIQY-UHFFFAOYSA-N
Last Updated: 2025-10-28 10:54
