Compound Q&A
How is [2-(Benzyloxy)-5-chlorophenyl]boronic acid (CAS: 612832-83-4) typically synthesized?
Answer
![[2-(Benzyloxy)-5-chlorophenyl]boronic acid](https://static.chemtradehub.com/structs/612/612832-83-4-d33b.webp "[2-(Benzyloxy)-5-chlorophenyl]boronic acid")
[2-(Benzyloxy)-5-chlorophenyl]boronic acid (CAS: 612832-83-4) is typically synthesized via a condensation reaction between 5-chlorobenzoic acid and benzyl alcohol, followed by boronation using a boronate ester. Common catalysts include sodium hydride and potassium tert-butoxide, with high selectivity and yield. The reaction is performed under an inert atmosphere to prevent oxidation and side reactions.
About
CAS No
612832-83-4
English Name
[2-(Benzyloxy)-5-chlorophenyl]boronic acid
Molecular Formula
C13H12BClO3
Molecular Weight
262.5 g/mol
SMILES
ClC1=CC=C(OCC2=CC=CC=C2)C(B(O)O)=C1
InChIKey
SLERXVFZNNSBIX-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24
![[2-(Benzyloxy)-5-chlorophenyl]boronic acid — ShangHaiJiZhiShengHua Technology Co Ltd](https://static.chemtradehub.com/suppliers/67cecbee2b2de6e8e95a5b72/67cecbee2b2de6e8e95a5b72-logo.webp){kind=logo}
![[2-(Benzyloxy)-5-chlorophenyl]boronic acid — Shanghai Jixiang Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce6f4d2b2de6e8e95a45bf/67ce6f4d2b2de6e8e95a45bf-logo.webp){kind=logo}
![[2-(Benzyloxy)-5-chlorophenyl]boronic acid — HePeng （ ShangHai ） Biotechnology Co Ltd](https://static.chemtradehub.com/suppliers/67ceccf22b2de6e8e95a5e0f/67ceccf22b2de6e8e95a5e0f-logo.webp){kind=logo}
![[2-(Benzyloxy)-5-chlorophenyl]boronic acid — JiangSuAiKangShengWuYiYaoYanFa Co Ltd](https://static.chemtradehub.com/suppliers/67cec9452b2de6e8e95a52fa/67cec9452b2de6e8e95a52fa-logo.webp){kind=logo}
![[2-(Benzyloxy)-5-chlorophenyl]boronic acid — Jin Jinle (Hunan) Chemical Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce76192b2de6e8e95a464e/67ce76192b2de6e8e95a464e-logo.webp){kind=logo}