[2-(Benzyloxy)-5-chlorophenyl]boronic acid(CAS: 612832-83-4)

[2-(Benzyloxy)-5-chlorophenyl]boronic acid (CAS: 612832-83-4) is a crystalline solid with a molecular weight of approximately 294.04 g/mol. It has a low solubility in water but is more soluble in organic solvents such as methanol and dichloromethane. Chemically, it is reactive towards nucleophiles and can undergo boronate ester formations. It is stable under normal laboratory conditions but should be stored in a cool, dark place to prevent degradation.

[2-(Benzyloxy)-5-chlorophenyl]boronic acid (CAS: 612832-83-4) is typically synthesized via a condensation reaction between 5-chlorobenzoic acid and benzyl alcohol, followed by boronation using a boronate ester. Common catalysts include sodium hydride and potassium tert-butoxide, with high selectivity and yield. The reaction is performed under an inert atmosphere to prevent oxidation and side reactions.

[2-(Benzyloxy)-5-chlorophenyl]boronic acid (CAS: 612832-83-4) is used in the pharmaceutical industry for the synthesis of medicinal compounds, particularly in the development of anti-inflammatory and anticancer drugs. It is also utilized in the polymer industry for modifying polymer properties and in sensor technology for detecting specific chemical species. Additionally, it plays a role in semiconductor manufacturing as a precursor in metal organic chemical vapor deposition (MOCVD) processes.

When handling [2-(Benzyloxy)-5-chlorophenyl]boronic acid (CAS: 612832-83-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. The compound should be handled in a fume hood to prevent inhalation. In the event of a spill, immediately clean up using personal protective equipment and ensure proper disposal in accordance with local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.