Compound Q&A
How is 2,6-Bis(2-methyl-2-propanyl)-4-nitrophenol (CAS: 728-40-5) typically synthesized?
Answer
2,6-Bis(2-methyl-2-propanyl)-4-nitrophenol is typically synthesized through the nitration of 2,6-bis(2-methylpropyl)phenol. This involves treating the phenol with a mixture of nitric acid and sulfuric acid under controlled conditions. The reaction is carried out in a fume hood due to the generation of toxic gases. The yield is around 70-80%, and mild conditions are used to improve selectivity and reduce by-products.
About
CAS No
728-40-5
English Name
2,6-Bis(2-methyl-2-propanyl)-4-nitrophenol
Molecular Formula
C14H21NO3
Molecular Weight
251.32 g/mol
SMILES
CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)[N+](=O)[O-]
InChIKey
FCGKUUOTWLWJHE-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30
